Лучшая цена на sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer





Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that feature selected case studies describing recently introduced drugs or drug classes. These include small molecule drugs as well as biopharmaceuticals and range across different therapeutic fields. Together, they provide a representative cross-section of the present-day drug development effort. Successful Drug Discovery: Volume 4 covers trends in peptide-based drug discovery and the physicochemical properties of recently approved oral drugs. The section on drug class studies looks at antibody-drug conjugates and the discovery, evolution, and therapeutic potential of dopamine partial agonists. Featured case studies examine the discovery of Etelcalcetide for the treatment of secondary hyper-parathyroidism in patients with chronic kidney disease; the development of Lenvatinib Mesylate; the discovery and development of Venetoclax; and more. -Focuses on recently introduced drugs that have not been featured in any textbooks or general references, including Ocrelizumab, a new generation of anti-CD-20 mAb for the treatment of multiple sclerosis, and Venetoclax, a selective antagonist of BCL-2 -Features personal experiences of successful drug developers from industry and academia -Endorsed and supported by the International Union of Pure and Applied Chemistry (IUPAC) Successful Drug Discovery: Volume 4 provides a fascinating and informative look into the process of drug discovery and would be a great reference for those in the pharmaceutical industry, organic and pharmaceutical chemists, and lecturers in pharmacy.
Sara A. Hurvitz Antibody-Drug Conjugates. Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Guofeng You Drug Transporters. Molecular Characterization and Role in Drug Disposition sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Li Chun Drug Delivery Applications of Noninvasive Imaging. Validation from Biodistribution to Sites of Action sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Gerhard Friedrich Müller Protein Kinases as Drug Targets sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Lu Chuang Enzyme Inhibition in Drug Discovery and Development. The Good and the Bad sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Gerd Folkers Protein Therapeutics sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Yuliang Zhao Biomedical Nanomaterials sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Huang Xianhai Case Studies in Modern Drug Discovery and Development sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Binghe Wang Drug-Drug Interactions in Pharmaceutical Development sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Группа авторов Drug Discovery and Development, Volume 2 sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Christian Klein Successful Drug Discovery sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Toshihisa Ishikawa Pharmacogenomics of Human Drug Transporters. Clinical Impacts sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Zhou Honghui Drug-Drug Interactions for Therapeutic Biologics sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Группа авторов Principles of CNS Drug Development sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Elizabeth Kwong Oral Formulation Roadmap from Early Drug Discovery to Development sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Henry Riordan Critical Pathways to Success in CNS Drug Development sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Mitchell Cayen N. Early Drug Development. Strategies and Routes to First-in-Human Trials sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer
Minghan Wang Metabolic Syndrome. Underlying Mechanisms and Drug Therapies sara a hurvitz antibody drug conjugates fundamentals drug development and clinical outcomes to target cancer


  • Страница:   1 2 3 4 5 6 7 8 9 10 11 12 13